Entrez 85236 | Ensembl ENSG00000197903 | |
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Aliases HIST1H2BK, H2B/S, H2BFAiii, H2BFT, H2BK, histone cluster 1, H2bk External IDs MGI: 2448399 HomoloGene: 135980 GeneCards: HIST1H2BK |
Histone H2B type 1-K is a protein that in humans is encoded by the HIST1H2BK gene.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family. This gene is found in the histone microcluster on chromosome 6p21.33.
Interactions
HIST1H2BK has been shown to interact with HIRA.
References
HIST1H2BK Wikipedia(Text) CC BY-SA