Kalpana Kalpana

HIST1H2BH

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Species  Human
Entrez  8345
Human  Mouse
Ensembl  ENSG00000275713
HIST1H2BH
Aliases  HIST1H2BH, H2B/j, H2BFJ, histone cluster 1, H2bh
External IDs  MGI: 3702051 HomoloGene: 134772 GeneCards: HIST1H2BH

Histone H2B type 1-H is a protein that in humans is encoded by the HIST1H2BH gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

References

HIST1H2BH Wikipedia


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