Species Human Entrez 255626 | Human Mouse Ensembl ENSG00000146047 | |
Aliases HIST1H2BA, H2BFU, STBP, TSH2B, TSH2B.1, bA317E16.3, TH2B, histone cluster 1, H2ba External IDs MGI: 2448375 HomoloGene: 69356 GeneCards: HIST1H2BA | ||
Histone H2B type 1-A is a protein that in humans is encoded by the HIST1H2BA gene.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.
References
HIST1H2BA Wikipedia(Text) CC BY-SA