Girish Mahajan

HIRIP3

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Aliases  HIRIP3
Human  Mouse
Ensembl  ENSG00000149929
Species  Human
Entrez  8479
HIRIP3
External IDs  MGI: 2142364 HomoloGene: 18218 GeneCards: HIRIP3

HIRA-interacting protein 3 is a protein that in humans is encoded by the HIRIP3 gene.

The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism.

References

HIRIP3 Wikipedia


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