Species Human Entrez 3046 | Human Mouse Ensembl ENSG00000213931 | |
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Aliases HBE1, HBE, hemoglobin subunit epsilon 1 External IDs MGI: 96024 HomoloGene: 110794 GeneCards: HBE1 | ||
Hemoglobin subunit epsilon is a protein that in humans is encoded by the HBE1 gene.
Function
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5' - epsilon – gamma-G – gamma-A – delta – beta - 3'.
References
HBE1 Wikipedia(Text) CC BY-SA