Guay is a surname. Notable people with the surname include:
Albert Guay (1917–1951), resident of Quebec City, Canada
Annie Guay (born 1985), Canadian ice hockey player
Erik Guay (born 1981), Canadian alpine ski racer
Florian Guay, politician in Quebec
François Guay (born 1968), professional ice hockey centre
Jacob Guay (born 1999), Canadian young singer
Joseph-Philippe Guay (1915–2001), Canadian parliamentarian
Lucie Guay (born 1958), Canadian sprint kayaker
Monique Guay (born 1959), Quebec politician
Paul Guay (born 1963), American professional ice hockey player
Pierre Malcom Guay (1848–1899), physician, surgeon and political figure in Quebec
Raynald Guay (born 1933), Liberal party member of the Canadian House of Commons
Rebecca Guay, artist specializing in watercolor painting and illustration
Richard Guay (disambiguation), multiple people
Tom Guay, guitar player who joined White Zombie
