Guardian, in comics, may refer to:
Guardian (DC Comics), the alias of Jim Harper, a costumed hero
Guardian (Marvel Comics), the alias of James Hudson, a superhero
Guardian, the alias of Heather Hudson, wife of James Hudson, better known as Vindicator
Guardians, a Marvel Comics series
It may also refer to:
Guardian angel (comics), the superhero alias of Hop Harrigan
Guardians of the Galaxy, two Marvel Comics teams
Guardians of the Galaxy (1969 team)
Guardians of the Galaxy (2008 team)
Guardians of the Universe, DC Comics aliens who are behind the Green Lantern Corps
New Guardians, a DC Comics team picked by the Guardians of the Universe
Global Guardians, a DC Comics superhero team
Guardian (Mal Duncan), also known as Vox, Hornblower, and the Herald, a DC Comics superhero