Neha Patil

Growth factor like domain

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Symbol  APP_CU_bd
InterPro  IPR008154
SCOP  1mwp
Pfam  PF02177
SMART  SM00006
Growth factor-like domain

A growth factor-like domain (GFLD) is a protein domain structurally related to epidermal growth factor, which has a high binding affinity for the epidermal growth factor receptor. As structural domains within larger proteins, GFLD regions commonly bind calcium ions. A subtype present in the N-terminal region of the amyloid precursor protein is a member of the heparin-binding class of GFLDs and may itself have growth factor function, particularly in promoting neuronal development.


Growth factor-like domain Wikipedia

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