Grote Street is a major street in the CBD of the centre of Adelaide, South Australia. It runs in an east-west direction, as a continuation of Wakefield Street where it crosses Victoria Square. It concludes at West Terrace; the road which continues is Sir Donald Bradman Drive. The Grote Street–Sir Donald Bradman Drive route is the most direct method of travelling from the CBD to the Adelaide Airport.
It was named after George Grote, an English classical historian and supporter of Robert Gouger.
Grote Street is largely occupied by retail outlets, as well as St Patrick's Church and Her Majesty's Theatre. The rear entrance of the Adelaide Bus Station is located on this street. Given that the Moonta Street Chinatown is accessible via Grote Street, it is also home to some Chinese restaurants and other businesses owned by Chinese Australians and Korean Australians.
The northern entrance of the Adelaide Central Markets can also be found on Grote Street. A paifang, comprising an archway erected by the city council and two lions donated by the People's Republic of China, marks the northern entrance to the Chinatown.