Grizzard is a surname. Notable people with the surname include:
Frank E. Grizzard, Jr. (born 1954), American historian, writer, and documentary editor
George Grizzard (1928-2007), American actor
Herman Grizzard (died 1971), American radio disc jockey
Lewis Grizzard (1946-1994), American writer and humorist
Rod Grizzard (born 1980), American basketball player