Notable people with the surname Griscom include:
Betsy Ross, probably apocryphal designer of the American flag, born Elizabeth Phoebe Griscom
Chris Griscom, American alternative medicine healer
Clement Griscom, American shipping magnate, father of Frances C. Griscom
Deborah Griscom Passmore, American botanical illustrator
Frances C. Griscom, American amateur golfer, daughter of Clement Griscom
John Griscom, American educator
Ludlow Griscom, American ornithologist
Lloyd Carpenter Griscom, American diplomat
Tom Griscom, American newspaper editor
William Woodnut Griscom, American electrical engineer and founder of the Electro-Dynamic Company
