Grimes is a surname that is believed to be of a Scandinavian, English, or Irish descent, and may refer to:
Alison Lundergan Grimes (b. 1978), Kentucky Secretary of State
Aoibhinn Grimes (b. 1976), former field hockey forward from Canada
Ashley Grimes (disambiguation), multiple people
Barbara Grimes (d. 1957), teenage American murder victim - see Murder of the Grimes sisters
Brent Grimes (b. 1983), American football player
Bryan Grimes (1828–1880), major general in the Confederate Army during the U.S. Civil War
Burleigh Grimes (1893–1985), American baseball player
Camryn Grimes (b. 1990), American actress
Charles Grimes (surveyor) (1772–1858), English surveyor
Charles Grimes (rower) (1935–2007), American Olympic rower
Christopher M. Grimes (b. 1948), artist from Bermuda
Connor Grimes (b. 1983), American field hockey player
David Grimes (Alabama politician) (b. c. 1953), American politician
Edward Grimes (b. 1991), one of the twin performers in the duo known as Jedward (along with John Grimes)
Frank Grimes (actor) (b. 1947), Irish actor
Gary Grimes (b. 1955), American actor
Grimes (musician) (b. 1988), stage name of the Canadian musician Claire Elise Boucher
Henry Grimes (b. 1935), American jazz musician
Jack Grimes (disambiguation), multiple people
James W. Grimes (1816–1872), American politician
Jason Grimes (b. 1959), American long jumper
Jesse Grimes (1788–1866), Texas pioneer and politician of Grimes County Texas
John Grimes (disambiguation), multiple people
Joseph Rudolph Grimes (1923–2007), Liberian Secretary of State; Louis Arthur Grimes School of Law founder
Karolyn Grimes (b. 1940), American actress
Louis Arthur Grimes (1883–1948), tenth Chief Justice of Liberia
Ken Grimes (b. 1947), American artist
Mark Grimes, Toronto City Councillor
Martha Grimes (b. 1931), American writer of detective fiction
Oscar Grimes, Jr. (1915–1993), utility infielder in Major League Baseball
Patricia Grimes (d. 1957), teenage American murder victim - see Murder of the Grimes sisters
Paul Grimes (criminal) (b. 1950), former Liverpudlian gangster who became and informant in a witness protection program
Paul Grimes (public servant), contemporary senior Australian public servant and former Secretary of the Australian Government Department of Agriculture
Phil Grimes (1929–1989), Irish hurler
Ray Grimes, Sr. (1893–1953), first baseman in Major League Baseball
Roger Grimes (b. 1950), Canadian politician
Roy Grimes (1893–1954), second baseman in Major League Baseball
Scott Grimes (b. 1971), American actor
Shenae Grimes (b. 1989), Canadian-American actress
Steve Grimes, contemporary member of the British band The Farm
Stuart Grimes (b. 1974), former Scottish international rugby player and captain
Tammy Grimes (1934–2016), American actress and singer
Tiny Grimes (1916–1989), American jazz and R&B guitarist
Vic Grimes (b. 1970), American professional wrestler
W. F. Grimes (1905–1988), British archaeologist
Fictional characters:
John Grimes, the hero of a series of science fiction novels by A. Bertram Chandler
John Grimes, in the film Black Hawk Down
Morgan Grimes, major character on the television series Chuck
Muddy and Dallas Grimes, villains of the film Beavis and Butt-Head Do America
Rick Grimes, protagonist in the comic book and television series The Walking Dead
