Greenlees is a surname. Notable people with the surname include:
Don Greenlees (born 1875), Scottish footballer with St. Mirren and Southampton
Duncan Greenlees (1899–1966), theologist
Gavin Greenlees (1930–1983), Australian poet
James Greenlees (1878–1951), Scottish international rugby union captain and educationlist
Ysobel Greenlees (1902-1996), Scottish international golfer and founder of the Greenlees Trophy League