Grafton is both a surname and a given name. Notable people with the name include:
Surname:
Anthony Grafton, American historian
C. W. Grafton, American novelist
Frederick William Grafton, British industrialist and politician
Jimmy Grafton, English writer, producer and theatrical agent
Joseph Grafton, founder of the Newton Theological Institution
Peter Grafton, British Musician
Richard Grafton, English historian
Sue Grafton, American author
Given name:
Grafton D. Cushing, American politician
Grafton Green, American jurist
Grafton K. Mintz, American copy editor
Grafton Njootli, Canadian politician
Grafton Elliot Smith, Australian anatomist