In medicine, Goodell's sign is an indication of pregnancy. It is a significant softening of the vaginal portion of the cervix from increased vascularization. This vascularization is a result of hypertrophy and engorgement of the vessels below the growing uterus. This sign occurs at approximately 4 weeks gestation.
The sign is named after William Goodell.
References
Goodell's sign Wikipedia(Text) CC BY-SA