Entrez 2239 | Ensembl ENSG00000076716 | |
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Aliases GPC4, K-glypican, glypican 4 External IDs MGI: 104902 HomoloGene: 55582 GeneCards: GPC4 |
Glypican-4 is a protein that in humans is encoded by the GPC4 gene.
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
References
Glypican 4 Wikipedia(Text) CC BY-SA