Symbol Glyco_hydro_98M InterPro IPR013191 Pfam structures | Pfam PF08306 CAZy GH98 PDB RCSB PDB; PDBe; PDBj | |
In molecular biology, glycoside hydrolase family 98 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.
Members of glycoside hydrolase family 98 have endo-β-galactosidase activity. This family includes E-ABase from Clostridium perfringens which cleaves both blood group A and B glycotopes.
The putative catalytic domain is found to the N-terminus of a second domain, which is not expected to form part of the catalytic activity.