Symbol Glyco_hydro_52 InterPro IPR000852 Pfam structures | Pfam PF03512 CAZy GH52 PDB RCSB PDB; PDBe; PDBj | |
In molecular biology, glycoside hydrolase family 52 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.
Glycoside hydrolase family 52 CAZY GH_52 comprises enzymes with only one known activity; beta-xylosidase (EC 3.2.1.37).
Proteins harboring beta-xylosidase and xylanase activities have been identified in the Gram-positive, facultative thermophilic aerobe Bacillus stearothermophilus 21. This microbe, which functions in xylan degradation, can utilise xylan as a sole source of carbon. The enzyme hydrolyses 1,4-beta-D-xylans, removing successive D-xylose residues from the non-reducing termini. It also hydrolyses xylobiose.