Species Human Entrez 6536 | Human Mouse Ensembl ENSG00000196517 | |
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Aliases SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9 External IDs MGI: 95760 HomoloGene: 5050 GeneCards: SLC6A9 | ||
Sodium- and chloride-dependent glycine transporter 1 is a protein that in humans is encoded by the SLC6A9 gene.
Selective inhibitors
Elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders. Several drug candidates have reached clinical trials.
References
Glycine transporter 1 Wikipedia(Text) CC BY-SA