Girish Mahajan (Editor)

Glycerol dehydratase

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EC number
  
4.2.1.30

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9077-68-3

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a glycerol dehydratase (EC 4.2.1.30) is an enzyme that catalyzes the chemical reaction

glycerol 3-hydroxypropanal + H2O

Hence, this enzyme has one substrate, glycerol, and two products, 3-hydroxypropanal and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is glycerol hydro-lyase (3-hydroxypropanol-forming). Other names in common use include glycerol dehydrase, and glycerol hydro-lyase. This enzyme participates in glycerolipid metabolism. It employs one cofactor, cobalamin.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1IWP and 1MMF.

References

Glycerol dehydratase Wikipedia