Glycerol 3 phosphate 1 dehydrogenase (NADP )

In enzymology, a glycerol-3-phosphate 1-dehydrogenase (NADP⁺) (EC 1.1.1.177) is an enzyme that catalyzes the chemical reaction

sn-glycerol 3-phosphate + NADP⁺ ⇌ D-glyceraldehyde 3-phosphate + NADPH + H⁺

Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and NADP⁺, whereas its 3 products are D-glyceraldehyde 3-phosphate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is sn-glycerol-3-phosphate:NADP⁺ 1-oxidoreductase. Other names in common use include glycerol phosphate (nicotinamide adenine dinucleotide phosphate), dehydrogenase, L-glycerol 3-phosphate:NADP⁺ oxidoreductase, glycerin-3-phosphate dehydrogenase, NADPH-dependent glycerin-3-phosphate dehydrogenase, and glycerol-3-phosphate 1-dehydrogenase (NADP⁺).