EC number 2.3.2.15 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 125390-02-5 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a glutathione gamma-glutamylcysteinyltransferase (EC 2.3.2.15) is an enzyme that catalyzes the chemical reaction
glutathione + [Glu(-Cys)]n-GlyThus, the two substrates of this enzyme are glutathione and [Glu(-Cys)]n-Gly, whereas its two products are Gly and [Glu(-Cys)]n+1-Gly.
This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase. Other names in common use include phytochelatin synthase, and gamma-glutamylcysteine dipeptidyl transpeptidase.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2BTW and 2BU3.
References
Glutathione gamma-glutamylcysteinyltransferase Wikipedia(Text) CC BY-SA