EC number 2.6.1.15 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9030-44-8 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a glutamine-pyruvate transaminase (EC 2.6.1.15) is an enzyme that catalyzes the chemical reaction
L-glutamine + pyruvateThus, the two substrates of this enzyme are L-glutamine and pyruvate, whereas its two products are 2-oxoglutaramate and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-glutamine:pyruvate aminotransferase. Other names in common use include glutaminase II, L-glutamine transaminase L, and glutamine-oxo-acid transaminase. This enzyme participates in glutamate metabolism. It employs one cofactor, pyridoxal phosphate.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1V2D, 1V2E, and 1V2F.