EC number 2.6.1.16 ExPASy NiceZyme view | CAS number 9030-45-9 | |
Alt. names hexosephosphate aminotransferaseglucosamine-6-phosphate isomerase (glutamine-forming)glutamine-fructose-6-phosphate transaminase (isomerizing)D-fructose-6-phosphate amidotransferaseglucosaminephosphate isomeraseglucosamine 6-phosphate synthaseGlcN6P synthase | ||
In enzymology, a glutamine-fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.16) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are L-glutamine and D-fructose 6-phosphate, whereas its two products are L-glutamate and D-glucosamine 6-phosphate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-glutamine:D-fructose-6-phosphate isomerase (deaminating). This enzyme participates in glutamate metabolism and aminosugars metabolism.
Structural studies
As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes 1JXA, 1MOQ, 1MOR, 1MOS, 1XFF, 1XFG, 2BPL, 2J6H, 2POC, 2PUT, 2PUV, and 2PUW.