Glutamate—ethylamine ligase

In enzymology, a glutamate-ethylamine ligase (EC 6.3.1.6) is an enzyme that catalyzes the chemical reaction

The 3 substrates of this enzyme are ATP, L-glutamate, and ethylamine, whereas its 3 products are ADP, phosphate, and N5-ethyl-L-glutamine.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is L-glutamate:ethylamine ligase (ADP-forming). Other names in common use include N5-ethyl-L-glutamine synthetase, theanine synthetase, and N5-ethylglutamine synthetase.