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Glucose 6 phosphate 1 epimerase

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EC number
  
5.1.3.15

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37259-65-7

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a glucose-6-phosphate 1-epimerase (EC 5.1.3.15) is an enzyme that catalyzes the chemical reaction

alpha-D-glucose 6-phosphate beta-D-glucose 6-phosphate

Hence, this enzyme has one substrate, alpha-D-glucose 6-phosphate, and one product, beta-D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is D-glucose-6-phosphate 1-epimerase. This enzyme participates in glycolysis / gluconeogenesis.

Structural studies

As of late 2013, 3 structures have been solved for this class of enzymes, with PDB accession codes 2CIQ, 2CIR, and 2CIS.

References

Glucose-6-phosphate 1-epimerase Wikipedia


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