EC number 4.2.1.39 ExPASy NiceZyme view | CAS number 37290-75-8 | |
In enzymology, a gluconate dehydratase (EC 4.2.1.39) is an enzyme that catalyzes the chemical reaction
D-gluconate
Hence, this enzyme has one substrate, D-gluconate, and two products, 2-dehydro-3-deoxy-D-gluconate and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include D-gluconate dehydratase, and D-gluconate hydro-lyase. This enzyme participates in pentose phosphate pathway.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1QJ4.
References
Gluconate dehydratase Wikipedia(Text) CC BY-SA