Gish is a surname. Notable people with the surname include:
Annabeth Gish (born 1971), American actress
Dorothy Gish (1898–1968), American actress
Duane Gish (1921–2013), American biochemist and prominent creationist
Lillian Gish (1893–1993), American silent film actress
Lou Gish (1967–2006), British actress
Sheila Gish (1942–2005), British actress
Warren Gish, American computational biologist