Gillette is a surname. Notable people with the surname include:
Gillette (singer) (born 1974), full name Sandra Gillette, American R&B-dance artist
Anita Gillette (born 1936), American actress and game-show panelist
Arthur Gillette (1863–1921), American pediatric orthopedic surgeon
Chester Gillette (1883–1908), American murderer
Clarence Preston Gillette (1859–1941), American entomologist
Douglas W. Gillette (1918-1942), American naval officer
Elizabeth V. Gillette (1874–1965), New York physician, assemblywoman 1920
Guy Gillette (1879–1973), American politician from Iowa
Guy Gillette (photographer) (1922-2013), American photographer
Jim Gillette (born 1967), American singer
King Camp Gillette (1855–1932), American businessman and founder of the Gillette Safety Razor Company
William Gillette (1853–1937), American actor famous for his stage version of Sherlock Holmes
