Gilkey is a surname. Notable people with the surname include:
Art Gilkey (1926–1953), American geologist and mountaineer
Bernard Gilkey (born 1966), former Major League Baseball player
Bertha Gilkey (1949–2014), African-American activist of tenant management of public housing properties
Garrett Gilkey (born 1990), American football offensive guard
Gordon Gilkey (1912–2000), American artist, educator, and promoter of the arts from Oregon
Helen Margaret Gilkey (1886–1972), pioneering mycologist and botanist
Howard Gilkey (1890–1972), American landscape architect known for his civic works in Oakland, California
John Charles Gilkey, prolific book and document thief
John Gilkey, American actor, comedian, juggler and clown
Langdon Brown Gilkey (1919–2004), American Protestant Ecumenical theologian
Peter B. Gilkey (born 1946), American mathematician, working in differential geometry and global analysis
Randy Gilkey (born 1976), American singer, songwriter, multi-instrumentalist, producer and recording engineer
Richard Gilkey (1925–1997), American painter, often associated with the 'Northwest School' of artists