Giguère or Giguere is a surname. Notable people with the surname include:
Daniel Giguère (1957-), Canadian politician
François Giguère (1963-), former general manager of the Colorado Avalanche
Jean-Sébastien Giguère (1977-), Canadian hockey goaltender
Louis Giguère (1911-2002), Canadian senator
Nathalie Giguère (1973-), Canadian swimmer
Paul-Antoine Giguère (1910-1987), Canadian academic and chemist
Réal Giguère (1933-), Canadian talk and game show host
Robert Giguère (1616-1709) early pioneer in New France
Samuel Giguère (1985-), Canadian football player
