Germacrene A alcohol dehydrogenase

Updated on Dec 17, 2024

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EC number 1.1.1.314 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Germacrene A alcohol dehydrogenase (EC 1.1.1.314) is an enzyme with systematic name germacra-1(10),4,11(13)-trien-12-ol:NADP⁺ oxidoreductase. This enzyme catalyses the following chemical reaction

germacra-1(10),4,11(13)-trien-12-ol + 2 NADP⁺ + H₂O ⇌ germacra-1(10),4,11(13)-trien-12-oate + 2 NADPH + 3 H⁺ (overall reaction)(1a) germacra-1(10),4,11(13)-trien-12-ol + NADP⁺ ⇌ germacra-1(10),4,11(13)-trien-12-al + NADPH + H⁺(1b) germacra-1(10),4,11(13)-trien-12-al + NADP⁺ + H₂O ⇌ germacra-1(10),4,11(13)-trien-12-oate + NADPH + 2 H⁺

In Lactuca sativa this enzyme is a mutifunctional enzyme with EC 1.14.13.123.

References

Germacrene A alcohol dehydrogenase Wikipedia

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