Geranylfarnesyl diphosphate synthase

Updated on Nov 21, 2023

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EC number 2.5.1.81 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Geranylfarnesyl diphosphate synthase (EC 2.5.1.81, FGPP synthase, (all-E) geranylfarnesyl diphosphate synthase, GFPS, Fgs) is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 1 isopentenyl unit). This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate + isopentenyl diphosphate ⇌ (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate

The enzyme from Methanosarcina mazei is involved in biosynthesis of the polyprenyl side-chain of methanophenazine.

References

Geranylfarnesyl diphosphate synthase Wikipedia

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