Harman Patil (Editor)

Gavilimomab

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Type
  
Whole antibody

Target
  
CD147

CAS Number
  
244096-20-6

Source
  
Mouse

ATC code
  
none

ChemSpider
  
none

Gavilimomab (also known as ABX-CBL) is a mouse monoclonal antibody intended for use as an immunosuppressive biologic treatment of glucocorticoid-resistant graft versus host disease. It binds to the antigen CD147. Gavilimomab proved slightly less effective than standard antithymocyte globulin therapy.

It was originally developed by Abgenix, which was later acquired by Amgen.

References

Gavilimomab Wikipedia