Garin is a surname. Notable people with the surname include:
André Garin (1822–1895), American Roman Catholic priest
Erast Garin (1902–1980), Russian actor
Eugene Garin (1922–1994), Ukrainian painter and artist
Geoff Garin (born 1953), American political consultant
Hermes Garín (born 1947), Uruguayan Roman Catholic bishop
Hernán Garin (born 1983), Argentine footballer
Janette Garin, Filipino politician
Maurice Garin (1871–1957), French cyclist
Nikolai Garin-Mikhailovsky (1852–1906), Russian writer
Oleg Garin (born 1966), Russian football coach and player
Vladimir Garin (1987–2003), Russian actor
Christian Garín (born 1996), Chilean tennis player
Fictional characters
Pyotr Petrovich Garin or Engineer Garin, the main character in Aleksey Tolstoy's novel The Garin Death Ray (also in the films The Hyperboloid of Engineer Garin and Failure of Engineer Garin)
Seth Garin, character in Richard Bachman's novel The Regulators