Gallate decarboxylase

In enzymology, a gallate decarboxylase (EC 4.1.1.59) is an enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, 3,4,5-trihydroxybenzoate, and two products, pyrogallol and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3,4,5-trihydroxybenzoate carboxy-lyase (pyrogallol-forming). Other names in common use include gallic acid decarboxylase, and gallate carboxy-lyase. This enzyme participates in benzoate degradation via coa ligation.