Galactose 1 dehydrogenase (NADP )

In enzymology, a galactose 1-dehydrogenase (NADP⁺) (EC 1.1.1.120) is an enzyme that catalyzes the chemical reaction

D-galactose + NADP⁺ ⇌ D-galactonolactone + NADPH + H⁺

Thus, the two substrates of this enzyme are D-galactose and NADP⁺, whereas its 3 products are D-galactonolactone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-galactose:NADP⁺ 1-oxidoreductase. Other names in common use include D-galactose dehydrogenase (NADP⁺), and galactose 1-dehydrogenase (NADP⁺). This enzyme participates in galactose metabolism.