Galactose 1 dehydrogenase

In enzymology, a galactose 1-dehydrogenase (EC 1.1.1.48) is an enzyme that catalyzes the chemical reaction

D-galactose + NAD⁺ ⇌ D-galactono-1,4-lactone + NADH + H⁺

Thus, the two substrates of this enzyme are D-galactose and NAD⁺, whereas its 3 products are D-galactono-1,4-lactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-galactose:NAD⁺ 1-oxidoreductase. Other names in common use include D-galactose dehydrogenase, beta-galactose dehydrogenase, and NAD⁺-dependent D-galactose dehydrogenase. This enzyme participates in galactose metabolism.