GWB-666, is the acronym for Great Western Beast 666, which is the central computer of the Unistat government in Robert Anton Wilson's Schrödinger's Cat trilogy, and surely has no connection or connotation to George W. Bush (but see gwb43.com), as said trilogy was published in 1985. Simon Moon is director of the GWB-666 project. Information in GWB-666's files was subsequently scanned by the Illuminati.
References
GWB-666 Wikipedia(Text) CC BY-SA