Species Human Entrez 2869 | Human Mouse Ensembl ENSG00000198873 | |
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Aliases GRK5, GPRK5, G protein-coupled receptor kinase 5 External IDs MGI: 109161 HomoloGene: 3879 GeneCards: GRK5 | ||
G protein-coupled receptor kinase 5 is an enzyme that in humans is encoded by the GRK5 gene.
Function
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
References
GRK5 Wikipedia(Text) CC BY-SA