Entrez 9380 | Ensembl ENSG00000137106 | |
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External IDs MGI: 1923488 HomoloGene: 49088 GeneCards: GRHPR |
Glyoxylate reductase/hydroxypyruvate reductase is an enzyme that in humans is encoded by the GRHPR gene.
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. GRHPR mutation analysis needs to pay attention to primer design, because allele dropout can cause false-positive result.
References
GRHPR Wikipedia(Text) CC BY-SA