Trisha Shetty (Editor)

GR 113808

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Covid-19
CAS Number  144625-51-4
IUPHAR/BPS  247
Formula  C19H27N3O4S
Molar mass  393.499 g/mol
PubChem CID  119376
ChemSpider  106623
3D model (Jmol)  Interactive image
GR-113808 httpsuploadwikimediaorgwikipediacommonsthu

GR-113808 is a drug which acts as a potent and selective 5-HT4 serotonin receptor antagonist. It is used in researching the roles of 5-HT4 receptors in various processes, and has been used to test some of the proposed therapeutic effects of selective 5-HT4 agonists, such as for instance blocking the nootropic effects of 5-HT4 agonists, and worsening the respiratory depression produced by opioid analgesic drugs, which appears to be partly 5-HT4 mediated and can be counteracted by certain 5-HT4 agonists.

References

GR-113808 Wikipedia


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