Entrez 2805 | Ensembl ENSG00000120053 | |
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Aliases GOT1, ASTQTL1, GIG18, cAspAT, cCAT, AST1, glutamic-oxaloacetic transaminase 1 External IDs MGI: 95791 HomoloGene: 1571 GeneCards: GOT1 | ||
Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene.
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
References
GOT1 Wikipedia(Text) CC BY-SA