EC number 5.1.3.18 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 72162-82-4 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a GDP-mannose 3,5-epimerase (EC 5.1.3.18) is an enzyme that catalyzes the chemical reaction
GDP-mannoseHence, this enzyme has one substrate, GDP-mannose, and one product, GDP-L-galactose.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is GDP-mannose 3,5-epimerase. Other names in common use include GDP-D-mannose:GDP-L-galactose epimerase, guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate, and L-galactose epimerase. This enzyme participates in ascorbate and aldarate metabolism.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2C54, 2C59, 2C5A, and 2C5E.
References
GDP-mannose 3,5-epimerase Wikipedia(Text) CC BY-SA