Species Human Entrez 9518 | Human Mouse Ensembl ENSG00000130513 | |
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Aliases GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB, growth differentiation factor 15 External IDs OMIM: 605312 MGI: 1346047 HomoloGene: 3576 GeneCards: GDF15 | ||
Growth/differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.
References
GDF15 Wikipedia(Text) CC BY-SA