Species Human Entrez 2644 | Human Mouse Ensembl ENSG00000137880 | |
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Aliases GCHFR, GFRP, HsT16933, P35, GTP cyclohydrolase I feedback regulator External IDs MGI: 2443977 HomoloGene: 3849 GeneCards: GCHFR | ||
GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene.
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
References
GCHFR Wikipedia(Text) CC BY-SA