Aliases GBP2 Ensembl ENSG00000162645 | Entrez 2634 | |
External IDs MGI: 102772 HomoloGene: 10289 GeneCards: GBP2 | ||
Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene.
Function
Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
References
GBP2 Wikipedia(Text) CC BY-SA