Frizzell is a surname. Notable people with the surname include:
Alan Frizzell (born 1995), Scottish footballerAndee Frizzell, actressColin Frizzell (born 1971), Canadian author of young adult novelsDavid Frizzell (born 1941), American Country Music SingerDavid Frizzell (Indiana politician), Republican member of the Indiana House of RepresentativesDick Frizzell (born 1943), New Zealand artistGregory Kent Frizzell (born 1956), United States federal judgeHenry F. Frizzell (1839–1904), Union Army soldier and Medal of Honor recipientJimmy Frizzell (1937–2016), former Scottish association football player and managerJohn Frizzell (born in Kingston, Ontario), Canadian screenwriter and film producerJohn Frizzell (composer) (born 1966), American film and television composerLefty Frizzell (1928–1975), American country music singer, songwriter and exponent of honky tonk musicMary Frizzell (1913–1972), Canadian athlete who competed in the 1932 Summer OlympicsWilliam Frizzell (born 1962), former American football defensive back