Freudenthal is a German surname. Notable people with the surname include:
Axel Olof Freudenthal (1836–1911), Finland-Swedish philologist, politician and racist.
Dave Freudenthal (born 1950), American politician
Franz Freudenthal, a Bolivian physician who is known for several medical inventions
Hans Freudenthal (1905–1990), Dutch mathematician
Heinrich Freudenthal, founder of Deutsche Pentosin-Werke GmbH
Jacob Freudenthal (1839-1907), German philosopher
Karl Freudenthal (died 1944), Nazi lawyer and SS officer
Matthijs Freudenthal, Dutch palaeontologist, former curator of fossil vertebrates of the National Museum of Natural History, Leiden, the Netherlands
Nancy D. Freudenthal (born 1954), U.S. district judge
Thor Freudenthal (born 1972), American director and screenwriter