Frank Walker may refer to:
Frank Arneil Walker (active from 2002), Scottish architectural academic and writer
Frank Buckley Walker (1889–1963), American talent agent
Frank Comerford Walker (1886–1959), former chairman of the Democratic National Committee
Frank R. Walker (1899–1976), American admiral during World War II
Frank T.O. Walker (1878–1904), Philippine–American War Medal of Honor recipient
Frank Walker (American football) (born 1981), American football cornerback
Frank Walker (Australian author) (born 1954), Australian journalist and non-fiction writer
Frank Walker (Australian journalist) (1919–2008), Australian journalist and non-fiction writer
Frank Walker (Australian politician) (1942–2012), former Member of the Australian House of Representatives and Member of the New South Wales Legislative Assembly
Frank Walker (Australian rules footballer) (born 1933), Australian rules footballer for Perth Football Club and Western Australia
Frank Walker (Scottish footballer)
Frank Walker (baseball) (1894–1974), Major League Baseball outfielder
Frank Walker (Jersey politician), former Chief Minister of the States of Jersey
Frank Walker (rugby league), rugby league footballer of the 1930s and 1940s
Frank X Walker (born 1961), American poet
Frank Ray Walker, architect, partner in the firm of Walker and Weeks
Frank Walker (lumberman) (1843–1916), lumberman, contractor and builder